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Sunday, October 31, 2010

U.S. intelligence trades on fear

Tehran, October 31: We are in the grip of yet another so-called terror plot designed to terrify the wits out of everyone.
Anyone of a nervous disposition was sent in to a tailspin of panic over the increasingly dramatic news coverage… this manifested itself in a tsunami of 911 calls in America which paralyzed parts of New York, Maine and Philadelphia for several hours, reports Tehran Times.

Mercifully in Britain the majority of us refuse to get caught up in this bloody nonsense for many different reasons. The primary one being we had already endured more than three decades of this during the height of the IRA activities in London.

Virtually every single day for 30 years there would be some terror alert in the English capital -- it was called shoestring terrorism. One telephone call could bring a halt to a section of the London Underground.

The police would make their necessary checks, the media would ignore it and we all got on with our lives refusing to be intimidated by Irish terrorism.

And that is exactly how we should have treated Friday’s terror nonsense -- that does not mean to say people should be reckless or less vigilant but governments should stop trying to impose a fear factor on its citizens.

We can not sacrifice our freedoms and liberties just because the United States wants to impose its own neurosis, hysteria and paranoia on the rest of the world.

While British anti-terror police say no explosives were found in a suspicious package found onboard a UPS flight, the White House issued a statement completely contradicting this. Now the parcel has been removed for full forensic testing!

Call me cynical, but I find it too much of a coincidence that this bizarre alert came less than 24 hours after British Airways chairman Martin Broughton has accused the country of bowing to U.S. demands for increased airport security measures.

Mr. Broughton criticized the U.S. for imposing more security checks on U.S.-bound flights, but not on its own domestic services.

He urged the UK to stop kowtowing to demands for passengers to take their shoes off and to put any laptop computers through scanners to be screened separately.

The UK government said it would give airport operators permission to review their security procedures and I hope they stick to their promise despite all this nonsense.

One of the most ridiculous procedures we have to go through is to submit all of our potions, lotions and liquids to airport security.

This came about because of the so-called plot to blow 10 airliners out of the sky. That the fools behind this crazy scheme didn’t even have passports or a collective IQ of George W. Bush mattered not.

A video was shown of an explosion onboard a plane if this chemical had been mixed with that chemical.

The fact the bombmakers would have had to create sub zero laboratory conditions onboard a plane which would take around 40 minutes, mattered not.

As a frequent flyer I can tell you no one would be allowed to hog the tiny toilets for more than five minutes.

Yet despite this nonsense we have to hand over our liquids, but can buy them in vast quantities minutes later having past through airport security.

Just recently I was stopped because I had a brand new 200ml jar of Eve Lom face cleanser and was told I could not take it through. I pleaded for some commonsense from the security officer and he even went to his superior when I pointed out that the jar cost more than my airline ticket.

A nearby passenger who had just wistfully given up his full bottle of Remy Martin brandy sympathized with me.

Since when did Eve Lom become a threat to Britain's national security?

The British Government’s COBRA emergency committee is meeting as I write this. God only knows what will transpire but I hope this coalition government distances itself from these crazy security terror alerts coming over from the Americans.

U.S. President Barack Obama is facing his mid-term elections this weekend… if either he or his team have resorted to the “terror threat” ploy so often used by his predecessor to try and win votes then shame on them.

Of course what better way to divert voters’ minds from Afghanistan, Iraq and Wikileaks than to create a fresh new bogeyman… Yemen.

Any government which uses security and fear to win votes does not deserve to be in power.

Yvonne Ridley is a presenter for Press TV's show The Agenda and co-presenter of the Rattansi & Ridley show.

Thursday, October 28, 2010

Why Kashmiris observe October 27 as Black Day!

by M Raza Malik
Kashmiris on both sides of the Line of Control and across the globe observe October 27 as Black Day and consider it as the blackest day in the history of Kashmir. This is the Day when India landed its army in Jammu and Kashmir, in total disregard to the Indian Independence Act and Partition Plan in 1947.

In order to change the demographic composition of the territory, Indian troops, the forces of Dogra Maharaja Hari Singh, and Hindu extremists massacred over three hundred thousand Kashmiri Muslims within a period of two months.

The Indian Independence Act and Partition Plan of 1947 had stated that the Indian British Colony would be divided into two sovereign states, India, with Hindu-majority areas, and Pakistan, with the Muslim-majority areas of Western provinces and east Bengal.

India by landing its Army in Jammu and Kashmir violated the guidelines set for deciding the future of Hyderabad, Junagarh and Kashmir, three of the independent Princely States at that time, which were given the choice to either accede to Pakistan or India, considering the geographical situation and communal demography. It forcibly occupied the Hyderabad and Junagarh, which had Hindus in majority but their rulers were Muslims. Kashmir was a Muslim-majority state and had a natural tendency to accede to Pakistan, but its Hindu ruler destroyed the future of Kashmiri people by announcing its accession to India under a controversial accession document (Instrument of Accession). Many neutral observers deny the existence of such document with the argument that had it been there Indian government had made it public either officially or at any international forum.

It is a historical fact that if the partition was done on the principles of Justice then India had no land route to enter into Jammu and Kashmir but the so-called Boundary Commission, headed by British Barrister, Cyril Radcliff, that demarcated partition line, under a conspiracy split Gurdaspur, a Muslim majority area, and handed it over to India, providing it terrestrial access to the territory.

Right from the day one, the people of Kashmir did not accept India's illegal occupation and started an armed struggle with the total support of public in 1948, which forced India to approach the UN Security Council to seek help of the World Body to settle the dispute. The UN Security Council through its successive resolutions nullified Indian invasion and occupation of Kashmir. It also approved a ceasefire, demarcation of the ceasefire line, demilitarization of the state and a free and impartial plebiscite to be conducted under the supervision of the World Body. Although the ceasefire and demarcation of the ceasefire line was implemented while demilitarization of the occupied territory and a free and impartial plebiscite under UN supervision remain unimplemented till date. As a result of the demarcation, about 139,000 square kilometers area of Jammu and Kashmir remained with India while 83,807 square kilometers constituted the territory of Azad Jammu and Kashmir.

Indian rulers promised before the UN to resolve the dispute and provide the people of Kashmir with their basic right of self-determination, but later backed away from their commitments. India has been putting peace, security and stability of the entire South Asia at stake by demonstrating continued rigidity and stubbornness and not responding positively to the efforts made by the international community to settle the Kashmir dispute during the last more than six decades.

Disappointed at the failure of all the efforts aimed at resolving the Kashmir dispute through peaceful means, the people of occupied Kashmir launched a massive uprising in 1989 to secure their right to self-determination. This movement gathered momentum with the passage of time and pushed the Indian authorities to wall, forcing them to sit around the negotiation table with Pakistan in January 2004. The talks process continued till it was hampered after Mumbai attacks on November 26, 2008, when India without any substantive evidence laid the responsibility of these attacks on Pakistan and its intelligence agencies. However, Prime Ministers of the two countries, Yousuf Raza Gilani and Manmohan Singh after a meeting at Sharm El-Sheikh, on July 16, 2009, in a joint statement declared to resume the composite dialogue process to resolve all outstanding issues.

It is worth mentioning that Pakistan demonstrated considerable flexibility in the dialogue process by floating various proposals including demilitarization, self-governance and joint-management to settle the conflict over Kashmir, but India's intransigent approach continued to remain the biggest hurdle in making successful any effort made in this regard. The ground situation in the occupied territory remains unchanged, as the confidence building measures and the dialogue process could not provide Kashmiri people respite from the Indian state terrorism.

India has exhausted all its resources and means but has not been able to deter Kashmiris from continuing their liberation struggle. It has given a free hand to its troops and police to subject peaceful protesters to brute force. Over 70 people were killed only within a period of two months in 2008 when Indian police personnel resorted to indiscriminate firing to break up demonstrators in Kashmir. The Chairman of All Parties Hurriyet Conference, Mirwaiz Umer Farooq was placed under house arrest for two months to prevent him from addressing public gatherings. Liberation leaders including Syed Ali Gilani, Shabbir Ahmed Shah, Aasiya Andrabi, Nayeem Ahmed Khan, Muhammad Ashraf Sehrai, Masarat Alam Butt and Muhammad Saleem Nunnaji have been booked under the infamous draconian law, Public Safety Act to keep them away from the people. The troops have been setting new records of human rights violations by killing innocent people, arresting youth, disgracing and harassing women and setting residential houses afire with impunity.

The troops have killed over ninety-two thousand Kashmiris, widowed more than twenty five thousand women, orphaned more than one hundred thousand children and molested or gang-raped around ten thousand Kashmiri women during the past 20 years. The whereabouts of thousands of innocent Kashmiris, disappeared in the custody of troops, are yet to be made known while hundreds of unnamed graves have been discovered in the occupied territory, which are believed to be of disappeared Kashmiris. This whole mayhem is being carried out with the protection of draconian laws, by virtue of which any person can be killed or put behind the bars without any accountability.

The All Parties Hurriyet Conference sources made a shocking revelation recently that in line with a new scheme, Indian troops were killing innocent Kashmiri youth in fake encounters in the areas near the Line of Control after arresting them from different parts of the occupied territory. According to the APHC sources through these killings India wanted to mislead the international community by propagating that Kashmiri youth were trying to enter Indian occupied Kashmir after crossing over the Line of Control.
The Amnesty International, Human Rights Watch, Asia Watch and other international humanitarian organizations in their regular reports over the unabated rights abuses in the occupied territory have been raising their concern. Even the European Union Parliament during its session in Strasbourg on July 10, 2008 unanimously passed a resolution calling upon the Indian Government to urgently conduct an independent and impartial probe into the issue of discovery of mass graves in the territory. It also strongly condemned unlawful killings, enforced disappearances, torture, rape and other human rights abuses, which have been taking place at the hands of the occupation troops in Jammu and Kashmir since 1989.

It was yet another exposition of India's callousness that the Prime Minister, Manmohan Singh on India's Independence Day, this year, tried to hoodwink the international community by stating that the elections in Kashmir had rendered the freedom element irrelevant. To protest this unrealistic statement Kashmiri people observed crippling strike on August 22. Pakistan's Foreign Minister, Shah Mehmood Qureshi while addressing a meeting of Kashmiri leaders on September 4, 2009 in Islamabad categorically emphasized that the elections in Indian occupied Kashmir could not be a substitute of Kashmiris' right to self-determination. He reaffirmed his country's moral, political and diplomatic support to Kashmir liberation movement. The mammoth anti-India protest demonstrations, participated by millions of people in Indian occupied Kashmir, last year, should be taken as Kashmiris' referendum against the Indian illegal occupation of their soil.

These are the reasons that why Kashmiris observe October 27 as Black Day. The observance is intended to send a loud and clear message to the international community to take cognizance of the miseries of Kashmiri people, help stop human rights violations in the occupied territory and play its role in bringing about a solution of the Kashmir dispute in accordance with Kashmiris' aspirations. It is also aimed at calling upon India to read writing on the wall, accept the ground realities and come forward with a realistic approach to settle the dispute for the larger interest of the people of the region.

(The writer is working as Senior Editor at Kashmir Media Service, Islamabad, and can be reached at razamalik849@yahoo.com) 

Wednesday, October 27, 2010

PIL against shutdowns, curfews


Srinagar, Oct 27:  The Public Interest Litigation (PIL)  filed by two NGOs last week against frequent shutdowns and imposition of curfews in the Valley has been listed for hearing before a Division Bench of High Court on November 2, reports Rissing Kashmir (26/10/2010)

The  PIL before was filed  by Jammu and Kashmir Tameer-e-Muashra Executive member Muhammad Sidiq Malik and Akhil Bharatiya Priyanka and Rahul Gandhi Foundation state president Ghulam Qadir Kullay on October 18. The PILs have sought court’s directions to separatist leaders not to disrupt normal life in the Valley by calling for frequent strikes and shutdowns.

The PIL has also made the Chief Secretary, the Home Secretary, the Director General of Police and the Additional DGP (Law and Order) as respondents  for imposing frequent curfews, which also disrupt normal life in Kashmir.

“ The PIL filed last week  has been listed  in the supplementary cause list before any  available Division Bench on next Tuesday (November 2),” sources in the High Court Registry told Rising Kashmir.

The litigants have sought court’s directions to prohibit Hurriyat (G) Chairman Syed Ali Geelani, Hurriyat (M) chairman Mirwaiz Umar Farooq  and Masrat Alam from issuing protest calendars.

“Frequent strikes and curfews have badly hit tourism and business sectors in the Valley and has crippled the education sector as well”, the litigants have submitted in the PIL.

Providing statistics and figures in support of its claims, the PIL states that shutdowns and resultant clashes have resulted in loss of over 100 precious lives and injuries to more than 8,500 people including 4,000 security men.

It is pertinent to mention here that High Court had played a pivotal role in ending over three month long strike of government employees by observing that there is “no fundamental, legal or statutory right for the employees to go on strike”.

The observations of HC’s Division Bench on  April 13 this year came after two lawyers approached the Court with a PIL, seeking indulgence  of the court in the sufferings and hardships  faced by the  public  due to the  indefinite strike called by government employees.

Saturday, October 23, 2010

Saffron (Crocus sativus L.) : Saffron is recommended for breast cancer

Saffron is recommended for breast cancer
Saffron (Crocus sativus L.) contains chemical constituents that are responsible for its color, flavor and aroma. Saffron contains numerous phytoactive components, including crocetin, various crocins (such as picrocrocin), zeaxanthin, lycopene, beta-carotene and safranal (the main component of saffron's fragrant essential oil). Saffron components have been shown to have strong antioxidant, anti-inflammatory, cytotoxic, anti-carcinogenic and anti-tumor properties, as well as reducing blood pressure, anxiety and depression.

Saffron is recommended for breast cancer
Saffron (Crocus sativus L.) contains chemical constituents that are responsible for its color, flavor and aroma. Saffron contains numerous phytoactive components, including crocetin, various crocins (such as picrocrocin), zeaxanthin, lycopene, beta-carotene and safranal (the main component of saffron's fragrant essential oil). Saffron components have been shown to have strong antioxidant, anti-inflammatory, cytotoxic, anti-carcinogenic and anti-tumor properties, as well as reducing blood pressure, anxiety and depression.

Breast cancer-related effects of eating saffron

Both saffron and crocin have been found to suppress DNA damage in a dose dependent manner in the livers, lungs, kidneys, and spleens of laboratory mice. Saffron has been shown to inhibit carcinogen-induced skin carcinoma in mice and to have cytotoxic action against human leukemia cell lines. Saffron also has been shown to cause cell death in HeLa and HepG2 liver cancer cells and TCC 5637 transitional cell carcinoma cells. Saffron extract and its constituent, crocin, have been shown to significantly inhibit the growth of colorectal cancer cells while not harming normal cells. Crocetin, a major carotenoid component of saffron, has been shown to have significant antiproliferative and proapoptic effects in pancreatic cancer cells in the laboratory and in laboratory mice. Saffron extract has been shown to have dose-dependent inhibitory effects on the proliferation of human MCF-7 and MDA-MB-231 breast cancer cells. Saffron has been found to greatly inhibit chemotherapy-induced cellular DNA damage. However, there is some evidence that saffron could be toxic at very high doses and we recommend consuming saffron as a spice and not taking saffron tablets.

Additional comments
Saffron is hand picked and hand processed, which is one reason for its high market price. Saffron is grown primarily in Iran, but it is also grown in Spain, Portugal, Italy, Kashmir and some parts of North Africa. Much of the Iranian production is redistributed through Spain. Saffron grown in these regions generally is grown without using pesticides. China is also beginning to produce saffron.

Meadow saffron (Colchicum autumnale), also known as wild saffron, Autumn crocus, or colchicum, is an unrelated and poisonous plant that should not be confused with saffron and is to be avoided. It can cause thirst, pain, diarrhea, weakness, vomiting, kidney failure, coma, and death from respiratory failure. Diluted fractions of meadow saffron are sometimes used in herbal remedies for gout and arthritis.

Saffron might interfere with Warfarin (coumadin) and other blood-thinning therapy since it has been shown to reduce platelet aggregation and thrombosis formation.

Selected breast cancer studies Flavonoids, Proanthocyanidins, and Cancer Risk: A Network of Case-Control Studies From Italy Nutrition and Cancer, October 2010
The present meta-analysis was designed to investigate the associations between dietary intake of flavonoids and proanthocyanidins and risks of various types of cancer. The meta-analysis analyzed data from multiple Italian case-control studies including approximately 10,000 incident, histologically confirmed cases of selected cancers and more than 16,000 cancer-free controls. Multiple logistic regression models were used to calculate odds ratios (ORs) for the highest compared to the lowest quintiles (fifths) of consumption of six classes of flavonoids and proanthocyanidins. Total intakes of flavonoids, flavanones, and flavonols were found to be inversely related to oral and laryngeal cancers (OR = 0.56 (oral cancer) and OR = 0.60 (laryngeal cancer) for total flavonoids; 0.51 (oral) and 0.60 (laryngeal) for flavanones; and 0.62 (oral) and 0.32 (laryngeal) for flavonols). Intake of flavanols was also found to be inversely related to laryngeal cancer (OR = 0.64), whereas intake of flavanones was inversely related to esophageal cancer (OR = 0.38). Reduced risk of colorectal cancer was associated with high intake of anthocyanidins (OR = 0.67), flavonols (OR = 0.64), flavones (OR = 0.78), and isoflavones (OR = 0.76). Inverse associations were also found between proanthocyanidins and colorectal cancer, especially for proanthocyanidins with a higher degree of polymerization (OR = 0.69 for ≥ 10 mers). No association between flavonoids and prostate cancer was found. A reduction in risk of breast cancer was found for high dietary intake of flavones (OR = 0.81) and flavonols (OR = 0.80). Common flavones include apigenin and luteolin (tricin is another flavone found primarily in brown rice). Common flavonols include quercetin, kaempferol and fisetin. Flavonols (OR = 0.63) and isoflavones (OR = 0.51) were found to be inversely associated with risk of ovarian cancer, whereas flavonols (OR = 0.69) and flavones (OR = 0.68) were inversely associated with renal cancer.

Circulating Carotenoids, Mammographic Density, and Subsequent Risk of Breast Cancer Cancer Research, November 2009

The present nested case-control study was designed to investigate whether the association between carotenoid consumption and risk of breast cancer is related to mammographic density. High breast density as measured by mammography has been reported to be a powerful indicator of increased breast cancer risk. The study included 604 breast cancer cases and 626 cancer-free controls in the Nurses' Health Study for whom circulating carotenoid (alpha-carotene, beta-carotene, beta-cryptoxanthin, lycopene, and lutein/zeaxanthin) levels had been measured and mammograms obtained prospectively. Using a computer-assisted method to determine mammographic density, circulating carotenoids were not found to be associated with mammographic density. However, mammographic density significantly influenced the association between total circulating carotenoids and risk of breast cancer (P heterogeneity = 0.008). Total circulating carotenoid levels were found to be inversely associated with overall breast cancer risk (P trend = 0.01). Among women in the highest third of mammographic density, total circulating carotenoids were associated with a 50% lower risk of breast cancer (odds ratio = 0.5; 95% confidence interval = 0.3 - 0.8). Similarly, among these women, high levels of circulating alpha-carotene, beta-cryptoxanthin, lycopene, and lutein/zeaxanthin were found to be associated with a significant 40% to 50% reduction in risk of breast cancer (P trend < 0.05). On the other hand, no such inverse association was observed between circulating carotenoids and breast cancer risk among study participants with low mammographic density. The authors conclude that plasma levels of carotenoids may play a role in reducing risk of breast cancer, especially among women with high breast density.

Crocetin inhibits pancreatic cancer cell proliferation and tumor progression in a xenograft mouse model Molecular Cancer

Therapeutics, March 2009

The present study was designed to determine whether crocetin, a unique carotenoid found in saffron, significantly affects pancreatic cancer growth. Crocetin was found to inhibit proliferation of MIA-PaCa-2 human pancreatic cancer cells. Crocetin also was found to alter the cell cycle proteins Cdc-2, Cdc-25C, and Cyclin-B1 and epidermal growth factor receptor, inhibiting proliferation. In vivo studies also were performed. Pancreatic cancer cells were injected into the right hind legs of athymic nude mice and crocetin was given orally to the mice after the development of a palpable tumor. Significant regression in tumor growth (with inhibition of proliferation) was found in the crocetin-treated animals compared to the control animals. The authors conclude that crocetin stimulated significant apoptosis in both in vitro pancreatic cancer cells and in vivo mice tumors.

Study of cytotoxic and apoptogenic properties of saffron extract in human cancer cell lines Food and Chemical Toxicology, November 2008

The present study was designed to evaluate the cytotoxic effect of saffron extract in HepG2 and HeLa liver cancer cell lines. Malignant liver cancer cells and non-malignant cells were cultured and incubated with varying concentrations of an ethanolic saffron extract. Saffron was shown to decrease cell viability in malignant cells in a dose- and time-dependent manner. Saffron also induced a sub-G1 peak in the flow cytometry histogram of saffron-treated cells compared to the controls, indicating apoptotic cell death was involved. This toxicity was found to be independent of ROS production. The authors conclude that saffron can cause cell death in HeLa and HepG2 liver cancer cells, and that apoptosis or programmed cell death plays an important role in this process.

Crocin from Crocus Sativus Possesses Significant Anti-Proliferation Effects on Human Colorectal Cancer Cells Experimental Oncology, September 2007

The anti-proliferative effects of Crocus sativus and its major component, crocin, on three colorectal cancer cell lines was examined in this study. Crocus sativus' effect on normal cells was also evaluated. The purity of crocin in the extract used was found to be 95.9% and the crocin content was 22.9%. The extract was found to significantly inhibit the growth of all three colorectal cancer cell lines (HCT-116, SW-480, and HT-29) in a dose-dependent manner (P < 0.01). Proliferation was reduced most significantly in HCT-116 cells; to 45.5% at 1.0 mg/ml and to 6.8 % at 3.0 mg/ml. The Crocus sativus extract also had significant anti-proliferative effects in non-small cell lung cancer cells. However, the extract did not significantly affect the growth of non-cancerous young adult mouse colon cells. The authors concluded that Crocus sativus extract and its major constituent, crocin, significantly inhibited the growth of colorectal cancer cells while not affecting normal cells.

Inhibition of breast cancer cell proliferation by style constituents of different Crocus species Anticancer Research, January 2007

Among the different species of Crocus, only the styles of Crocus Sativus L. have been studied extensively, since these constitute the well-known spice saffron. Saffron is widely used in Mediterranean, Indian and Chinese cuisine. In the present study, hydrophilic carotenoids in the styles of three other Crocuses endemic to Greece (C. boryi ssp. tournefortii, C. boryi ssp. boryi, and C. niveus) were discovered and reported on for the first time. Incubation of MCF-7 and MDA-MB-231 breast cancer cells for 48 hours with varying concentrations of extracts of all four styles was found to have a dose-dependent inhibitory effect on cell proliferation. The antiproliferative effect did not appear to be estrogen related. Studies on the effect of trans-crocin-4 (the main carotenoid constituent of C. sativus styles, digentibiosylester of crocetin), crocetin and safranal showed that the antiproliferative effect was attributable to crocin irrespective of the degree of glycosylation.

Subacute Toxicity of Crocus Sativus L. (Saffron) Stigma Ethanolic Extract in Rats American Journal of Pharmacology and Toxicology, 2007

The present study was designed to evaluate the possible toxic effects of an extract of Crocus sativus L. stigma on liver, kidney and selected hematological parameters in rats. Establishing the safety of saffron (Crocus sativus L.) is important since the medicinal properties attributed to it are extensive. Wistar rats were assigned to four groups of eight. The first group was designated the control. Groups 2, 3 and 4 were treated with an ethanolic extract of saffron in doses of 0.35, 0.70 and 1.05 g per kg, respectively, for two weeks. The body weights of the rats were measured on the first, seventh and final days of the study. Blood-related tests performed on the rats included total RBC count, total WBC count, Hb, %HCT, MCH, MCV and MCHC. Biochemical and serum profile tests included ALT, AST, urea, uric acid and creatinine. Tissue specimens of the rat livers and kidneys were also examined histologically. The extract was found to result in significant reductions in Hb and HCT levels and total RBC count, without a dose-dependent relationship. However, significant dose-dependent increases in total WBC count, ALT, AST, urea, uric acid and creatinine were found in extract-treated rats. Mild to severe liver and kidney tissue injuries were observe microscopically, supporting the biochemical analysis. The authors conclude that extract of Crocus sativus L. stigma is toxic in high doses.

Protective effect of saffron (Crocus sativus L.) aqueous extract against genetic damage induced by anti-tumor agents in mice Human & Experimental Toxicology, February 2006
The genotoxic potential of chemotherapy drugs limits their efficacy in the treatment of cancers. This study was designed to evaluate the chemoprotective potential of saffron against the toxicity of three well-known chemotherapy drugs, cisplatin, cyclophosphamide and mitomycin-C, using comet assay. Three doses of saffron (20, 40 and 80 mg/kg of body weight) were orally administered to mice for five days prior to dosing with the drugs under investigation. Pre-treatment with saffron was found to greatly inhibit chemotherapy drug-induced cellular DNA damage (i.e., strand breaks). The authors conclude that, together with previous study results, the findings suggest a potential role for saffron as an adjuvant in chemotherapeutic applications.
More details: http://foodforbreastcancer.com/foods/saffron
Fresh Crocus Sativus L. (Saffron) Stigma available at:
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